论文部分内容阅读
3-甲芬太尼是本所发现的芬太尼类型镇痛药中一种较强的药物,它的镇痛作用比芬太尼强2—19倍,而其急性与亚急性毒性却较小。本文合成羰基~(14)C标记的甲芬太尼(I)。
3-Fefentanil is a strong drug found in our fentanyl type analgesics. Its analgesic effect is 2 to 19 times stronger than that of fentanyl, but its acute and sub-acute toxicity is more small. In this paper, carbonyl ~ (14) C-labeled fentanyl (I) was synthesized.