药物处方的工艺任务,在于制备安全而治疗上等效的制剂。治疗等效就是含有一定量药物的制品,当用于一定的病症或一定的症状时,具有相等的效果和安全性。治疗上不等效的制品,尽管药物的化学含量完全相等,而其临床疗效却有差别。这从水难溶性药物中可以见到,现有的地高辛和洋地黄毒甙制剂即属此类。用强心甙作合理治疗,准确的剂量是个关键,因各人所需的剂量常与平均剂量偏离很大,如应用的制剂是治疗等效的,则在医师根据需要来变换药物时,可达最大的准确性。然而化学上等值的制剂,在临床上不一定等效。药物治疗中的剂量——作用关系,常是一个复杂的相互作用的过程。另一个用强心甙治疗的问题是制剂中主药的含量都很 The technical task of drug prescription lies in the preparation of safe and therapeutically equivalent preparations. Therapeutic equivalent is a product containing a certain amount of drug, which has equal efficacy and safety when used in certain conditions or certain symptoms. Therapeutically inequitable products, although the chemical content of the drug is exactly the same, but its clinical efficacy is different. This can be seen in poorly water-soluble drugs. The existing digoxin and digoxin preparations belong to this category. With cardiac glycosides as a reasonable treatment, the exact dose is a key, because each dose often deviate from the average dose, such as the application of the preparation is equivalent to treatment, the physician in accordance with the need to change the drug may be The greatest accuracy. However, chemically equivalent preparations are not necessarily equivalent clinically. The dose-effect relationship in drug therapy is often a complex process of interaction. Another problem with the treatment of cardiac glycosides is the formulation of the main drug content are