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核医学在临床肿瘤学中的最主要作用是肿瘤显像,包括估计特异器官或全身是否存在肿瘤。本文试图介绍当前核医学检查用于客观评价局部和全身化疗恶性病变的情况。局部化疗一、~(99m)锝-大颗粒白蛋白(~(99m)Tc-MAA)灌注闪烁扫描用于动脉内化疗:评价缓慢滴注化疗药物分布的最好方式是使用~(99)mTc-MAA(通常1~2mCi/0.2~0.5ml),其注射速率接近化疗药物的滴注速率。MAA 颗粒的分布(大多为10~90μm)通常与血液以及化疗药物的分布方式类同。
The main role of nuclear medicine in clinical oncology is tumor imaging, including the estimation of the presence of tumors in specific organs or in the body. This article attempts to introduce the current nuclear medicine examination for the objective evaluation of local and systemic chemotherapy malignant lesions. Local Chemotherapy, ~(99m)PrM-(99m)Tc-MAA Perfusion Scintigraphy for Intraarterial Chemotherapy: The Best Way to Assess Slow Dispensing Chemotherapy Drug Distribution is to Use ~(99)mTc - MAA (usually 1 to 2 mCi/0.2 to 0.5 ml) with an injection rate close to the infusion rate of the chemotherapeutic agent. The distribution of MAA particles (mostly 10 to 90 μm) is generally similar to that of blood and chemotherapeutic agents.