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实验动物中,自发性膀胱癌是罕见的。根据模型的制作方法,膀胱癌动物模型可分为两大类,一类是移植膀胱癌模型,另一类是化学致癌剂诱发的膀胱癌模型。所谓移植膀胱癌模型是将人和动物膀胱癌组织或细胞移植刘动物体内,制成异位或正常解剖部位的膀胱癌模型。来自人的膀胱癌组织通常被移植到无胸腺裸鼠皮下,在体外培养的人膀胱癌细胞可接种在裸鼠皮下和膀胱腔内,亦可由裸
In experimental animals, spontaneous bladder cancer is rare. According to the method of making the model, animal models of bladder cancer can be divided into two categories, one is a model of bladder cancer transplanted and the other is a model of bladder cancer induced by chemical carcinogens. The so-called transplanted bladder cancer model is the human and animal bladder cancer tissue or cell transplantation Liu animals, made ectopic or normal anatomical parts of the bladder cancer model. Human bladder cancer tissues are usually transplanted subcutaneously in athymic nude mice. Human bladder cancer cells cultured in vitro can be inoculated subcutaneously in the nude mice and in the bladder cavity,