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在阐述logistic模型分析毒物联合作用的基本原理的基础上,以两种毒物联合作用为例,用这一模型评价联合作用的性质、确定其剂量-反应关系和LD50集合及其相应的95%置信区域,具有客观和适用范围广的特点,为毒物联合作用的深入研究提供了一种新的方法。
Based on the analysis of the basic principles of the logistic model for the analysis of the joint effects of poisons, taking the combined action of two poisons as an example, the model was used to evaluate the properties of the combined effects and to determine the dose-response relationship and LD50 aggregation and their corresponding 95% confidence The region has the characteristics of being objective and applicable. It provides a new method for further research on the joint action of poison.