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目的探讨使用低分子肝素钙及降纤酶治疗急进性脑梗死的疗效。方法 200例急性脑梗死患者随机分成2个组,每组100例,发病在48 h以内,治疗组采用低分子肝素钙治疗10 d(肝素3 000 U),对照组使用降纤酶10 U,连续静脉滴注3 d。结果 28 d后分析2组神经功能缺损差异有统计学意义(P<0.05)。结论使用低分子肝素钙及降纤酶治疗进展型脑梗死安全、有效、方便,应为首选药物之一。
Objective To explore the use of low molecular weight heparin and defibrase in the treatment of acute cerebral infarction. Methods 200 patients with acute cerebral infarction were randomly divided into two groups, 100 cases in each group, the incidence of less than 48 h, the treatment group with low molecular weight heparin treatment of 10 d (heparin 3000 U), the control group using defibrase 10 U, Continuous intravenous infusion of 3 d. Results After 28 days, the difference of neurological deficit between the two groups was statistically significant (P <0.05). Conclusion The use of low molecular weight heparin and defibrase in the treatment of advanced cerebral infarction is safe, effective and convenient and should be one of the first choice drugs.