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花生四烯酸代谢在很多生理与病理过程中起着重要的作用,国内外学者已报道了心脑血管疾病时的改变,但大多限于测定血浆前列腺素水平。最近我们观察了白细胞、血小板与血浆多种花生四烯酸代谢的改变,并探讨了这些变化的病理与临床意义。材料与方法急性脑血栓病人13例,年龄42～76岁,脑溢血病人19例,年龄45～78岁,有典型的脑卒中临床症状与体征,均经CT 扫描证实诊断与定位。冠心病病人13例,年龄46～78岁,其中急性心肌梗塞(AMI)5例,非AMI 8例,有
Arachidonic acid metabolism in many physiological and pathological processes play an important role, domestic and foreign scholars have reported changes in cardiovascular and cerebrovascular diseases, but mostly limited to the determination of plasma prostaglandin levels. We recently observed a variety of leukocyte, platelet and plasma changes in arachidonic acid metabolism, and to explore the pathological and clinical significance of these changes. MATERIALS AND METHODS Thirteen patients with acute cerebral thrombosis, aged 42-76 years and 19 with stroke, aged 45-78 years, had typical clinical signs and symptoms of stroke and were confirmed by CT scanning. Thirteen patients with coronary heart disease, aged 46 to 78 years, of which 5 cases of acute myocardial infarction (AMI), 8 cases of non-AMI, there