三组分偶联法已经在ＰＧＥ类化合物的合成中显示了极大的的优越性。由三组分偶联法合成ＰＧＥ类化合物的关键是Ｒα链的引入．目前经过化学家们的不断努力，该方法得到了不断的发展和完善，已经成为最成功的、有着良好应用前景的合成ＰＧＥ类化合物的方法．本文对三组分偶联法在ＰＧＥ类化合物合成中的研究进展情况做一综述 The three-component coupling method has shown great superiority in the synthesis of PGE-like compounds. The key to the synthesis of PGE compounds by three-component coupling is the introduction of Rα chain. At present, through continuous efforts of chemists, this method has been continuously developed and perfected and has become the most successful and promising method for synthesizing PGE compounds. This review summarizes the research progress in the synthesis of PGEs by the three-component coupling method