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目的观察丙泊酚、芬太尼静脉复合麻醉下联合米索前列醇应用于人工流产手术的疗效。方法将自愿要求终止妊娠的160例正常早孕妇女随机分为观察组和对照组。观察组80例在人流术中采用微量芬太尼、丙泊酚复合麻醉下联合米索前列醇进行镇痛、镇静麻醉、扩宫。对照组80例采用丙泊酚静脉麻醉。观察两组术中镇痛效果、宫颈软化度、手术时间、术中出血量、丙泊酚平均用量及人工流产综合征发生率。结果观察组丙泊酚平均用量明显减少,镇痛显效率和宫颈充分软化比率明显高于对照组(P(0.01),手术时间短,术中出血量少,两组比较差异有统计学意义(均P(0.05)。结论丙泊酚、芬太尼联合米索前列醇应用于无痛人工流产术,镇静镇痛效果确切,宫颈软化明显,手术时间短,出血少,并降低丙泊酚用量,具有可行性。
Objective To observe the curative effect of propofol and fentanyl combined with misoprostol under intravenous anesthesia in induced abortion. Methods 160 normal pregnant women who volunteered for termination of pregnancy were randomly divided into observation group and control group. Observation group of 80 cases of abortion in the abortion with a small amount of fentanyl, propofol anesthesia combined with misoprostol analgesia, sedation anesthesia, dilation. Control group, 80 cases of propofol intravenous anesthesia. The analgesic effect, cervical softening degree, operation time, intraoperative blood loss, average propofol dosage and incidence of induced abortion syndrome were observed in two groups. Results The average dosage of propofol in the observation group was significantly decreased, and the effective rate of analgesia and full softening of the cervix were significantly higher than those in the control group (P <0.01). The operation time was short and the intraoperative blood loss was small. There was significant difference between the two groups (P0.05) .Conclusion Propofol, fentanyl combined with misoprostol in painless artificial abortion, the exact analgesic effect of sedation, cervical softening obvious, short operation time, less bleeding, and reduce the dosage of propofol , Is feasible.