论文部分内容阅读
目的探讨腹膜透析(PD)与血液透析(HD)对尿毒症患者贫血的影响。方法 115例尿毒症患者按照透析方式不同分为PD组55例、HD组60例,PD组执行持续非卧床PD方案,采用葡萄糖浓度为1.5%和2.5%的PD液,二者比例为3∶1,每日换液8 000 m L,每周透析7 d。HD组采用HD,每周3次,每次4 h。以实验开始为起点,两组均持续透析8周,测定两组透析前后血清红细胞计数(RBC)、血红蛋白(Hb)、ALB(ALB)、C反应蛋白(CRP)、甲状旁腺激素(PTH),以及铁代谢指标,如血清铁(SI)、铁蛋白(SF)、转铁蛋白(TF)、转铁蛋白饱和度(TSAT%),并进行比较。结果透析前两组血清RBC、HB、ALB、PTH、CRP及铁代谢指标比较,P均>0.05;同组内透析前后各指标比较,P<0.05;透析后与HD组比较,PD组血清RBC、Hb升高,ALB、PTH、CRP、SF水平低(P均<0.05)。结论 PD对尿毒症患者贫血状态的改善优于HD。
Objective To investigate the effects of peritoneal dialysis (PD) and hemodialysis (HD) on anemia in uremic patients. Methods One hundred and fifteen patients with uremia were divided into three groups: PD group (55 cases) and HD group (60 cases). Patients in PD group underwent continuous ambulatory PD (PD) with glucose concentrations of 1.5% and 2.5% 1, daily exchange 8 000 mL, dialysis 7 d per week. HD group using HD, 3 times a week, each time 4 h. Starting from the beginning of the experiment, the two groups were continuously dialyzed for 8 weeks. Serum red blood cell count (RBC), hemoglobin (ALB), C-reactive protein (CRP), parathyroid hormone (PTH) , And iron metabolism indicators such as serum iron (SI), ferritin (SF), transferrin (TF), transferrin saturation (TSAT%), and compared. Results Before dialysis, serum RBC, HB, ALB, PTH, CRP and iron metabolism index of the two groups before dialysis were compared, P> 0.05; before and after dialysis in the same group, , Hb increased, ALB, PTH, CRP, SF levels were low (all P <0.05). Conclusion The improvement of anemia in patients with uremia is better than that of HD.