本文评价重组α2干扰素(IFN-α2)预防经常复发的生殖器单纯疱疹病毒(HSV)感染的效果和安全性。选择76名曾感染过HSV、并在前一年有8次以上再发的健康成人作为试验对象,随机分为3组,分别皮下注射3×10~6位IFN-α2(23人),1×10~6单位IFN-α2(16人)和安慰剂(37人),每周3次,共注射36次。其中8人因注射次数少于30次未作效果分析。记录再发时间,进行临床评价和病毒分离,一次 This article evaluates the efficacy and safety of recombinant alpha 2 interferon (IFN-α2) in preventing herpes simplex virus (HSV) infections that frequently recur. Sixty-six healthy adults who had been infected with HSV and who had had more than eight recurrences in the previous year were randomly divided into three groups: subcutaneous injection of 3 × 10 -6 IFN-α2 (23), 1 × 10 ~ 6 units of IFN-α2 (16) and placebo (37) three times a week for a total of 36 injections. Eight of them had no effect analysis because their number of injections was less than 30. Record recurrence time, clinical evaluation and virus isolation, once