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目的观察硫酸镁、乌拉地尔对重度子痫前期剖宫产术后患者降压治疗中的作用。方法对我院产科重症病房收治的106例重度子痫前期剖宫产术后患者进行随机分组,对照组为单用乌拉地尔组,试验组为硫酸镁+乌拉地尔组,两组均对用药后3h血压进行评价,对两组的ICU住院天数、乌拉地尔泵入总量及72h阴道出血量进行比较。结果对照组和试验组的降压满意率显示出统计学差异(P<0.05),两组的ICU住院天数、乌拉地尔泵入总量及72h阴道出血量未显示出统计学差异(P>0.05)。结论乌拉地尔在治疗子痫前期剖宫产术后患者过程中显示出了良好的降压效果,且硫酸镁的解痉治疗在本研究中显示出与乌拉地尔降压的协同作用。
Objective To observe the effect of magnesium sulfate and urapidil on antihypertensive treatment in patients with severe preeclampsia after cesarean section. Methods A total of 106 patients with severe preeclampsia undergoing cesarean section were randomly divided into control group, urapidil group and magnesium sulfate + urapidil group The blood pressure was evaluated 3h after treatment, and the days of ICU stay, the total amount of Urapidil and the amount of vaginal bleeding 72h were compared. Results There was a statistically significant difference between the two groups in the length of hospital stay, the total amount of Urapidil and the amount of vaginal bleeding in 72 hours (P> 0.05). Conclusion Urapidil shows good antihypertensive efficacy in the treatment of post-cesarean section patients with preeclampsia and the antispasmodic treatment of magnesium sulfate shows a synergistic effect with the antihypertensive effect of urapidil in this study.