【目的】探索本地区咳嗽变异性哮喘(cough variant asthma,CVA)儿童食物不耐受情况,为咳嗽变异性哮喘儿童的病因诊断、预防和治疗提供新的实验室参考依据。【方法】随机选取门诊咳嗽变异性哮喘患儿65例,正常对照74例,检测其血清中14种食物特异性IgG抗体并对结果进行统计分析。【结果】患者组食物特异性IgG抗体阳性率为90.77%,明显高于对照组的21.62%,两组比较差异有高度统计学意义(P<0.001)。忌食不耐受食物后,患者症状明显好转。【结论】食物特异性IgG抗体测定有助于及早发现咳嗽变异性哮喘患者的病因,为诊治和预防提供依据。 【Objective】 To explore food intolerance in children with cough variant asthma (CVA) in our region and to provide a new laboratory reference for the diagnosis, prevention and treatment of children with cough variant asthma. 【Methods】 Sixty-five children with cough-variant asthma were randomly selected in this study. Totally 74 control subjects were included in this study. Fourteen food-specific IgG antibodies in serum were detected and the results were statistically analyzed. 【Results】 The positive rate of food-specific IgG antibody in patients was 90.77%, which was significantly higher than that in control group (21.62%). There was a statistically significant difference between the two groups (P <0.001). After eating intolerant food, the patient’s symptoms improved significantly. 【Conclusion】 Food-specific IgG antibody is helpful to detect the etiology of cough-variant asthma early and provide evidence for diagnosis and treatment.