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目的研究钬激光治疗单纯性尿道狭窄与传统开放手术治疗尿道狭窄的疗效比较.方法选取我科2009年4月至2011年10月收治的患者120例,随机分为观察组与对照组,每组各60例,观察组采用钬激光联合电切术,对照组采用传统开放手术.比较两组的手术时间、术中出血量、尿管置留时间、最大尿流率及并发症.结果观察组在手术时间、术中出血量、尿道扩张次数、尿管置留时间方面明显优于对照组,有显著差异性(p<0.05).观察组术后有1例出现尿失禁,对照组术后有5例出现尿失禁,1例出现阳痿,两组比较有明显差异(p0.05).观察组有2例复发,对照组有3例复发,两组比较无明显差异.结论钬激光联合电切治疗单纯性尿道狭窄能缩短手术时间、减少术中出血量,加快患者恢复,较传统开放手术有明显优势,在适应症明确的情况下,值得应用.“,”Objective: To study the clinical effect of treating urethrostenosis with holmium laser compared traditional open surgery. Methods: Choosed 120 patients from Apr. 2009 to Oct. 2011 to divide into study group and controled group with 60 cases in each other. Study group were treated with holmium laser, controled group were treated with traditional open surgery. Compared the operation time, amount of bleeding, urine tube indweling time, maximum flow rate and complication. Results: The operation time, amount of bleeding, urine tube indweling time in study group were better than controled group. There was no difference in maximum flow rate in these two groups. There was 2 relapsed in study group and 3 relapsed in controled group. Conclusion: treating urethrostenosis with holmium laser can shorten the operation time reduce the intraoperative blood loss, speed up the patients recovery, better than traditional open to extend in clinical.