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目的观察沙眼衣原体(CT)感染与精浆锌(Zn)、铜(Cu)和超氧化物歧化酶(SOD)含量的关系。方法应用精子活体染色技术和Zn、Cu,SOD含量检测试剂盒,分别检测52例正常生育男性(正常对照组)和58例CT感染不育男性(CT感染组)的精子存活率与精浆Zn、Cu、SOD活性。结果CT感染组中精子存活率、精浆Zn、Cu、SOD含量较正常对照组显著降低(P<0.01)。结论CT感染可引起精浆Zn、Cu、SOD含量降低,精子膜发生氧化损伤,影响精子的存活率和活动力。
Objective To investigate the relationship between the infection of Chlamydia trachomatis (CT) and the contents of zinc, copper and superoxide dismutase (SOD) in seminal plasma. Methods Sperm biopsies and Zn, Cu, SOD assay kit were used to detect the sperm survival rate in 52 normal pregnant women (control group) and 58 CT infertile men (CT infection group) , Cu, SOD activity. Results In the CT infection group, the sperm motility and the contents of Zn, Cu and SOD in the seminal plasma were significantly lower than those in the normal control group (P <0.01). Conclusion CT infection can cause the content of seminal plasma Zn, Cu, SOD decreased, sperm membrane oxidative damage, affecting sperm survival and activity.