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目的:观察消旋卡多曲颗粒治疗婴幼儿轮状病毒肠炎的疗效及不良反应。方法:将112例轮状病毒肠炎患儿随机分成治疗组60例和对照组52例,治疗组在对照组常规治疗基础上加用消旋卡多曲颗粒,观察其疗效及不良反应。结果:两组的总有效率分别为93.33%、71.15%,差异有统计学意义(2χ=9.73,P<0.01)。治疗组疗程(6.02±1.12)d,对照组疗程(7.28±1.51)d,两组比较差异有统计学意义(t=5.06,P<0.01)。结论:消旋卡多曲颗粒治疗婴幼儿轮状病毒肠炎有利于减轻腹泻症状和缩短病程。
Objective: To observe the efficacy and adverse reactions of racecadotril granules in the treatment of infantile rotavirus enteritis. Methods: One hundred and twelve children with rotavirus enteritis were randomly divided into treatment group (n = 60) and control group (n = 52). The treatment group was treated with racecadotril on the basis of routine treatment in the control group. The curative effect and adverse reactions were observed. Results: The total effective rates of the two groups were 93.33% and 71.15%, respectively, with statistical significance (2χ = 9.73, P <0.01). The treatment group (6.02 ± 1.12) d, the control group (7.28 ± 1.51) d, the difference between the two groups was statistically significant (t = 5.06, P <0.01). Conclusion: Racecadotril granules for the treatment of infantile rotavirus enteritis is helpful to reduce the symptoms and shorten the course of diarrhea.