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目的：探讨丙种球蛋白联合糖皮质激素治疗特发性血小板减少性紫癜的临床效果，以供临床参考。方法将我院2010年8月至2012年7月收治的特发性血小板减少性紫癜患者63例纳入本研究，随机分组。对照组接受糖皮质激素，实验组接受大剂量丙种球蛋白联合糖皮质激素，对比两组患者治疗效果。结果与对照组对比，我们发现实验组患者治疗总有效率较高，为93.9%，而对照组为80.0%，组间差异经统计学分析后认为有意义（p＜0.05）结论大剂量丙种球蛋白联合糖皮质激素治疗特发性血小板减少性紫癜效果满意，值得推广。“,”Objective To investigate the gamma globulin combined clinical effect of glucocorticoid treatment of idiopathic thrombocytopenic purpura, and for clinical reference. Methods to reduce our hospital from August 2010 to July 2013 were treated idiopathic thrombocytopenic purpura in 63 patients enroled in the study were randomized. The control group received corticosteroids, the experimental group received high-dose gamma globulin combined with glucocorticoids, compared two groups of patients with the therapeutic effect. The results compared with the control group, we found that treatment of patients in the experimental group had a higher total efficiency of 93.9%, while the control group was 80.0%, the difference between groups was significant after statistical analysis (p <0.05) Conclusion large doses of gamma globulin protein combined with glucocorticoids treatment of idiopathic thrombocytopenic purpura satisfactory, worthy of promotion.