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小细胞肺癌(SCLC)常发生骨髓转移,但其对预后的意义和骨髓活检的实用价值尚有争议。作者对SCLC 病人做了回顾性分析,以评价在癌症分期中骨髓检查的用途,进而确定骨髓转移对预后的意义,同时阐明预示骨髓转移的血液学及生物化学变化。作者对129例 SCLC 病人作了骨髓检查,发现39例(30％)有骨髓转移,仅3例(2.3％)骨髓转移是唯一的转移部位。有、无骨髓转移两组病人比较,其血清乳酸脱氢酶(LDH)、谷草转氨酶(SGOT)、
Small cell lung cancer (SCLC) often undergoes bone marrow metastasis, but its significance for prognosis and the practical value of bone marrow biopsy are controversial. The authors performed a retrospective analysis of patients with SCLC to evaluate the use of bone marrow tests in cancer staging to determine the significance of bone marrow metastasis for prognosis and to elucidate hematological and biochemical changes that predict bone marrow metastases. The authors performed a bone marrow examination of 129 patients with SCLC and found that 39 (30%) had bone marrow metastases, and only 3 (2.3%) bone marrow metastases were the only sites of metastasis. Comparison of serum lactate dehydrogenase (LDH) and aspartate aminotransferase (SGOT) in patients with and without bone marrow metastasis