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多发性骨髓瘤系免疫细胞增殖性疾病,以浆细胞在骨髓中呈瘤性浸润为特征。本病自然病程仅为6～12个月,化疗可使其生存期延长5～7倍。现根据本院收治的30例,对其预后因素略加讨论。诊断与分型诊断条件本文30例的诊断均符合下列三项条件中任何二条:①骨髓象中浆细胞比值达10%以上;②血清中出现单株球蛋白(M 成分);③骨髓X 线拍片可见多个圆形钻孔样损害。分期分型根据骨骼损害程度分为三期,Ⅰ期:骨质疏松;Ⅱ期:溶骨损伤;Ⅲ期:广泛溶骨损伤加骨折。根据血尿素氮分为二型,A 型血尿素氮<30mg/dl;B 型血尿素氮>30mg/dl。
Multiple myeloma Department of immune cell proliferative diseases, characterized by plasmacytoid tumor cells in the bone marrow infiltration. The natural course of the disease is only 6 to 12 months, chemotherapy can extend the survival of 5 to 7 times. According to the hospital admitted 30 cases, its prognostic factors slightly discussed. Diagnosis and classification of diagnostic conditions 30 cases of this diagnosis are in line with any of the following three conditions in any one: ① bone marrow like plasma cells in the ratio of 10% or more; ② Serum monoclonal antibody (M component); ③ bone marrow X-ray Film shows a number of circular drilling damage. Staging according to the degree of bone damage is divided into three phases, Ⅰ: osteoporosis; Ⅱ: osteolytic injury; Ⅲ: extensive osteolytic injury plus fracture. According to the blood urea nitrogen divided into two types, type A blood urea nitrogen <30mg / dl; type B blood urea nitrogen> 30mg / dl.