本研究首次应用先进的浓度梯度PAGE技术,对卵巢良、恶性肿瘤及正常健康人各35份血清标本进行LDH同工酶分析。结果卵巢恶性组血清LDH阳性率为82.7％,卵巢良性组血清LDH假阳性率为25.7％。卵巢恶性组、卵巢良性组和正常人组血清同工酶谱之间有明显区别。作者认为,同时检测血清LDH及其同工酶,既可提高卵巢恶性肿瘤早期诊断的敏感性和特异度,又可鉴别卵巢恶性肿瘤的类型。 In this study, the first time using advanced concentration gradient PAGE technology, good and malignant ovarian tumors in 35 serum samples for LDH isoenzyme analysis. Results The positive rate of serum LDH in ovarian malignant group was 82.7%. The positive rate of LDH in benign ovarian group was 25.7%. Ovarian malignant group, benign ovarian group and normal group of serum isozyme between the significant difference. The authors believe that the simultaneous detection of serum LDH and its isozymes, can improve the sensitivity and specificity of early diagnosis of ovarian cancer, but also identify the type of ovarian cancer.