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小坂等在罔山地区对流行性肝炎进行长期追踪观察的结果,在75例急性肝炎中10年以后发现肝硬变者有3例,占3.6％。10年以后到20年有1例。近年来对乙型肝炎有关的抗原抗体检验成功以来,认为在成年人中初次感染肝炎病毒HBs抗原可以出现一过性阳性,难以认为是基本治愈的慢性肝炎的进展。已经证明慢性肝炎患者HBs抗原多数持续阳性。著者等在HBs抗原持续阳性的病例中,由病理证实先由急性肝炎以后发展的慢性肝炎的
As a result of long-term follow-up of epidemic hepatitis in Mt. Misato, Kawasaka et al. Found that in 10 of 75 cases of acute hepatitis, 3 cases were found to have cirrhosis after 3.6 years. In 10 years to 20 years in 1 case. In recent years, hepatitis B-related antigen and antibody test was successful since the initial infection in adults with hepatitis B virus HBs antigen can be considered transient positive, it is difficult to consider the progress of the basic cure of chronic hepatitis. It has been demonstrated that the majority of HBs antigens in patients with chronic hepatitis continue to be positive. Author, etc. In the case of HBs antigen persistently positive, pathologically confirmed chronic hepatitis with subsequent development of acute hepatitis