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目的 :本文运用现代分子生物学技术 ,检测糖尿病大鼠胰岛Ｂ细胞ＳＵＲ的ｍＲＮＡ的表达水平 ,旨在探讨二甲双胍对其影响及其二甲双胍的作用机制。探讨二甲双胍对糖尿病大鼠胰腺Ｂ细胞中ＳＵＲ的影响。方法 :ＳＤ大鼠 1 50～ 2 50ｇ,雄性 ,按随机原则把 40只大鼠分成二组 ,每组
OBJECTIVE: To detect the expression of SUR mRNA in pancreatic islet B cells of diabetic rats by using modern molecular biology techniques, and to explore the effect of metformin and its mechanism of action on metformin. To investigate the effect of metformin on SUR of B cell of pancreas in diabetic rats. METHODS: Forty male Sprague-Dawley rats weighing 150-250 g were randomly divided into two groups of 40 rats