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目的研究住院病人肠球菌感染的临床分布特点及其耐药性,为控制肠球菌感染提供依据。方法采用细菌分离鉴定和药敏试验方法,对某医院临床送检标本肠球菌分离鉴定和药敏试验相关资料进行回顾性统计分析。结果从该医院住院患者送检标本中共检出肠球菌263株,其中粪肠球菌133株,屎肠球菌114株,其它肠球菌16株。主要分离自尿液、伤口分泌物和血液。临床分离的粪肠球菌对氨苄西林、青霉素、环丙沙星、左氧氟沙星、呋喃妥因有较高的敏感性,屎肠球菌对多数抗菌药物呈现耐药,仅对万古霉素、替考拉林、氯霉素有较高的敏感性。结论该医院临床分离的肠球菌属感染以粪肠球菌和屎肠球菌为主,后者耐药性高于前者,高度关注耐万古霉素的肠球菌的出现。
Objective To study the clinical distribution and drug resistance of enterococcal inpatients in order to provide a basis for controlling enterococcal infection. Methods Bacterial isolation and identification and drug susceptibility testing methods were used to retrospectively analyze the isolation and identification of drug-susceptible enterococci in clinical specimens from a hospital. Results A total of 263 enterococci were detected in the inpatients of the hospital, including 133 strains of Enterococcus faecalis, 114 strains of Enterococcus faecium and 16 strains of other enterococci. Mainly isolated from urine, wound secretions and blood. Enterococcus faecalis isolates of ampicillin, penicillin, ciprofloxacin, levofloxacin, nitrofurantoin have a higher sensitivity, Enterococcus faecium showed resistance to most antibiotics, only vancomycin, teicoplanin, chlorine Mycin has a high sensitivity. Conclusion Enterococcus faecalis and Enterococcus faecium are the main clinical isolates of enterococci in the hospital. The latter is more resistant than the former, which is highly concerned with the emergence of vancomycin-resistant enterococci.