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目的观察布地奈德在儿童咳嗽变异性哮喘中的应用效果及对血清IgE的影响。方法选择本院咳嗽变异性哮喘患儿共80例,随机分为观察组和对照组。除了给予常规治疗外(对照组采用常规治疗),观察组患儿给予布地奈德吸入治疗。观察两组患儿治疗前后IgE水平改变情况和治疗效果。结果观察组治疗后IgE水平低于对照组治疗后,差异有统计学意义(P<0.05);观察组治疗后总有效率为95.0%,对照组治疗后总有效率为75.0%,观察组总有效率高于对照组,差异有统计学意义(P<0.05)。结论布地奈德在儿童咳嗽变异性哮喘中的应用效果显著,能够降低IgE水平,值得借鉴。
Objective To observe the effect of budesonide in children with cough variant asthma and its effect on serum IgE. Methods Eighty children with cough variant asthma were randomly divided into observation group and control group. In addition to the conventional treatment (control group, conventional treatment), the observation group was given budesonide inhalation therapy. The change of IgE level before and after treatment and the treatment effect were observed in both groups. Results The level of IgE in the observation group was lower than that in the control group (P <0.05). The total effective rate was 95.0% in the observation group and 75.0% in the control group. The total observation group Efficacy than the control group, the difference was statistically significant (P <0.05). Conclusions Budesonide has a significant effect in children with cough variant asthma, which can reduce IgE levels and is worth learning from.