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目的应用宫颈液基细胞学技术检测宫颈病变,寻找提高子宫颈癌前病变及宫颈癌的检出率的最有效途径。方法随机抽取2279例就诊病人进行TCT检查分析。细胞学诊断采用TBS分级系统。细胞学诊断阳性者,全部在阴道镜下取活组织检查,所有检查均在双盲下进行。结果除12例不满意标本外,TCT异常者检出率为8.43%(191/2267);其中ASCUS占5.03%(114/2267),鳞状上皮内病变(SIL)及鳞状细胞癌(SCC)占3.40%(77/2267);低度鳞状上皮内病变(LSIL)占1.72%(39/2267),高度鳞状上皮内病变(HSIL)占1.59%(36/2267);宫颈鳞状细胞癌(SCC)占0.09%(2/2267)。结论细胞学筛查是诊断宫颈病变的重要方法,配合阴道镜下活检,能提高子宫颈癌前病变和宫颈早期浸润癌检出率,具有重要的临床意义。
Objective To detect cervical lesions by cervical liquid-based cytology and find the most effective way to improve the detection rate of cervical precancerous lesions and cervical cancer. Methods Totally 2279 patients were selected for TCT examination. Cytological diagnosis using TBS classification system. Positive cytology diagnosis, all under colposcope biopsy, all tests were carried out in double blind. Results The detection rate of TCT abnormalities was 8.43% (191/2267) except for 12 cases of unsatisfactory specimens. Among them, ASCUS accounted for 5.03% (114/2267), squamous intraepithelial lesion (SIL) and squamous cell carcinoma (SCC) ) Accounted for 3.40% (77/2267); low grade squamous intraepithelial lesion (LSIL) accounted for 1.72% (39/2267), high grade squamous intraepithelial lesion (HSIL) accounted for 1.59% (36/2267) Cell carcinoma (SCC) accounted for 0.09% (2/2267). Conclusion Cytological screening is an important method to diagnose cervical lesions. Combined colposcopy biopsy can improve the detection rate of cervical precancerous lesions and early invasive carcinoma of the cervix, which has important clinical significance.