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新近研究显示CD4+CD25+调节性T细胞的分化过程及其功能在一定条件下存在可塑性。这不仅体现了机体免疫调节机制的复杂性,而且还提示该过程与炎症、自身免疫性疾病和肿瘤等临床疾病的发生发展过程密切相关。本文就其相关研究进展做一综述。
Recent studies have shown that the differentiation of CD4 + CD25 + regulatory T cells and their function under certain conditions exist plasticity. This not only reflects the complexity of the mechanism of immune regulation, but also suggests that the process is closely related to the occurrence and development of clinical diseases such as inflammation, autoimmune diseases and tumors. This article reviews its related research progress.