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目的:观察重组人干扰素α-2b凝胶联合消疣汤预防尖锐湿疣CO_2激光治疗术后复发的疗效。方法:72例患者随机分为2组。对照组予以CO_2激光治疗,术后3天予以干扰素α-2b凝胶外抹,每天3次。观察组在对照组治疗基础上加用消疣汤口服,每天1剂,水煎后分早晚2次内服。2组均连用6周。随访6月评估其痊愈率、复发率、复发时间和治疗中药物不良反应。结果:随访6月。观察组痊愈率高于对照组,复发率低于对照组,复发时间短于对照组。2组比较,差异均有统计学意义(P<0.05)。2组不良反应比较,差异无统计学意义(P>0.05)。结论:重组人干扰素α-2b凝胶联合消疣汤预防尖锐湿疣CO_2激光治疗术后复发的疗效确切,可减少其术后复发,延长复发时间,且具有较好的安全性。
Objective: To observe the effect of recombinant human interferon α-2b gel combined with wu wu decoction in preventing postoperative recurrence of condylomata acuminatum. Methods: 72 patients were randomly divided into two groups. The control group was given CO2 laser treatment, and the interferon alpha-2b gel was smeared externally 3 times a day after operation for 3 times. Observation group in the control group based on the use of Xiao Tong decoction plus oral, 1 day, decoction after oral administration 2 times sooner or later. 2 groups were used in conjunction for 6 weeks. Follow-up in June to assess the cure rate, recurrence rate, recurrence time and treatment of adverse drug reactions. Results: Follow-up in June. The recovery rate of the observation group was higher than that of the control group, the recurrence rate was lower than that of the control group, and the recurrence time was shorter than that of the control group. The differences between the two groups were statistically significant (P <0.05). There was no significant difference in adverse reactions between the two groups (P> 0.05). Conclusion: Recombinant human interferon α-2b gel combined with wu wu decoction can prevent postoperative recurrence of condylomata acuminatum, which can reduce the postoperative recurrence and prolong the relapse time and has good safety.