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目的:探讨微卫星分析在中国人膀胱癌诊断中应用的可行性;建立中国人膀胱癌诊断的微卫星组合。方法:选取分布于18条染色体上的60个微卫星位点对44例膀胱肿瘤病人的尿沉渣和新鲜肿瘤组织DNA进行分析,寻找能检出膀胱癌最多的位点组合;用此组合对26例膀胱肿瘤及1
Objective: To explore the feasibility of microsatellite analysis in the diagnosis of bladder cancer in Chinese and to establish a microsatellite combination for the diagnosis of bladder cancer in Chinese. Methods: Sixty microsatellite loci distributed on 18 chromosomes were selected to analyze urinary sediment and fresh tumor tissue DNA from 44 patients with bladder cancer, and to find the most likely locus for detecting bladder cancer. With this combination, Cases of bladder cancer and 1