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目的:代谢综合征及高危代谢综合征人群是颈动脉粥样硬化斑块形成的危险群体,聚集了多种心血管危险因素,易发生冠心病等心血管疾病,本研究利用超声波检测中膜内膜厚度的方法,检测了300例患者的颈动脉情况,以此探讨颈动脉内膜中膜厚度与代谢综合征的危险因素,对代谢综合征患者的心血管事件起到预测作用。方法:对300名研究对象均进行身高、体重、腰围、臀围及血压的测量,并于清晨空腹采静脉血检测空腹血糖、总胆固醇、低密度脂蛋白胆固醇及甘油三酯。体重指数=体重(kg)除以身高(m)2。采用HDI–5000型彩色多普勒超声仪行颈动脉内膜–中膜厚度测量,探头中心频率为10MHz,由专人操作,同步记录心电图。结果:代谢综合征组颈动脉内膜中膜厚度明显高于对照组。讨论:颈动脉内膜中膜厚度增厚已被证实与心血管危险因素以及冠状动脉粥样硬化的严重程度有密切相关性,且能可靠地预测未来心血管事件。
Aims: Metabolic syndrome and high-risk metabolic syndrome are risk groups for the formation of carotid atherosclerosis plaques. They accumulate a variety of cardiovascular risk factors and are prone to cardiovascular diseases such as coronary heart disease. In this study, The thickness of the carotid artery was measured in 300 patients to explore the intima-media thickness of the carotid artery and the risk factors of metabolic syndrome, and to predict the cardiovascular events in patients with metabolic syndrome. Methods: The height, body weight, waist circumference, hip circumference and blood pressure of 300 subjects were measured. Fasting blood glucose, total cholesterol, LDL cholesterol and triglyceride were measured in fasting venous blood at early morning. BMI = weight (kg) divided by height (m) 2. The carotid intima-media thickness was measured by HDI-5000 color Doppler ultrasound system. The center frequency of the probe was 10MHz. The ECG was recorded synchronously by hand. Results: The intima-media thickness of carotid artery was significantly higher in the metabolic syndrome group than in the control group. Discussion: The intima-media thickness of the carotid artery has been shown to be closely related to cardiovascular risk factors and the severity of coronary atherosclerosis and to reliably predict future cardiovascular events.