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目的:观察经验方健脾化瘀合剂加全肝移动条放射治疗原发性巨块型肝癌的临床疗效。方法:以前瞻、随机、单盲、对照法分为治疗组(健脾化瘀合剂加全肝移动条放射)32例,对照组(单纯放疗结合西医药疗法)30例。结果:治疗组与对照组近期疗效总缓解率分别为59.4%和36.7%(P>0.05);疼痛缓解程度比较,总有效率分别为81.1%和63.3%;生活质量变化比较:治疗组与对照组提高及稳定分别为87.5%和50%,两组患者0.5年、1年生存率分别为76.7%、43.3%和44%、24%。中位生存期分别为7.2个月和4.5个月。两组比较差异有显著性(P<0.05)。结论:健脾化瘀合剂加全肝移动条放射治疗原发性巨块型肝癌能缓解局部疼痛,提高生活质量,延长生存时间;并有稳定瘤体的作用,可有效地控制病情及延缓病情发展。
Objective: To observe the clinical efficacy of prescription Fang Jianpi Huayu Mixture plus whole liver moving strip radiotherapy in the treatment of primary giant hepatocellular carcinoma. Methods: The prospective, randomized, single-blind and control groups were divided into the treatment group (Jianpi Huayu Mixture plus whole liver moving strip radiation) 32 cases, the control group (radiotherapy combined with western medicine therapy) 30 cases. Results: The total effective rates of the treatment group and the control group were 59.4% and 36.7%, respectively (P> 0.05). The pain relief rates were 81.1% and 63.3%, respectively. The quality of life of the treatment group and the control group The improvement and stability of the two groups were 87.5% and 50% respectively. The 0.5-year and 1-year survival rates of the two groups were 76.7%, 43.3%, 44% and 24%, respectively. Median survival was 7.2 months and 4.5 months respectively. There was significant difference between the two groups (P <0.05). Conclusion: Jianpi Huayu Mixture and whole liver moving strip radiotherapy can effectively alleviate the local pain, improve the quality of life and prolong the survival time; and stabilize the tumor, which can effectively control the disease and delay the disease development of.