人干扰素epsilon(IFN-ε)属于Ⅰ型干扰素,具有抗病毒、抗肿瘤、免疫调节等生物学作用,目前国内外对其研究不多,是一种有待开发的新型干扰素。本文就IFN-ε的基因结构、表达方式、表达位置、受体、受体配体的作用途径、生物学作用以及临床应用的前景等方面,进行了比较系统的归纳和总结。 Human interferon epsilon (IFN-ε) belongs to the type I interferon and has the biological functions of antivirus, antitumor, immunomodulation and so on. So far it has not been much studied at home and abroad. It is a novel interferon to be developed. This article systematically summarized and summarized the gene structure, expression pattern, expression location, receptor, receptor ligand of IFN-ε, its biological function and the prospect of clinical application.