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为比较头孢噻肟加灭滴灵术前1次用药与标准的术前、术后3次用药,预防结直肠手术感染的效果,在14所医院对1018名各类型结直肠手术患者进行随机分组的对比研究。甲组在麻醉诱导期打开腹腔前5～10分钟,静脉给予头孢噻肟1g+灭滴灵500mg。乙组在术前同样时间静脉给予头孢噻肟1.5g+灭滴灵500mg。再于术后8及12小时分别给予头孢噻肟750mg+灭滴灵500mg。结果有943人得到最后评价。甲组伤口感
In order to compare the effect of cefotaxime and metronidazole administered once before and 3 times before surgery to prevent the infection of colorectal surgery, 1018 patients with various types of colorectal surgery were randomized in 14 hospitals Comparative study. Group A in the induction of anesthesia 5 to 10 minutes before opening the abdominal cavity, intravenous cefotaxime 1g metronidazole 500mg. Group B was intravenously given cefotaxime 1.5 g and metronidazole 500 mg at the same time before surgery. And then at 8 and 12 hours after cefotaxime 750mg metronidazole 500mg. 943 people got the final evaluation. A group of wounds