Subthalamic nucleus deep brain stimulation has become a standard neurosurgical therapy for advanced Parkinson’s disease. Subthalamic nucleus deep brain stimulation can dramatically improve the motor symptoms of carefully selected patients with this disease. Surprisingly, some specific dimensions of quality of life, “psychological” aspects and social adjustment do not always improve,and they could sometimes be even worse. Patients and their families should fully understand that subthalamic nucleus deep brain stimulation can alter the motor status and time is needed to readapt to their new postoperative state and lifestyles. This paper reviews the literatures regarding effects of bilateral subthalamic nucleus deep brain stimulation on social adjustment, quality of life and coping strategies in patients with Parkinson’s disease. The findings may help to understand the psychosocial maladjustment and poor improvement in quality of life in some Parkinson’s disease patients. Subthalamic nucleus deep brain stimulation has become a standard neurosurgical therapy for advanced Parkinson’s disease. Subthalamic nucleus deep brain stimulation can improve improve the motor symptoms of carefully selected patients with this disease. aspects and social adjustment do not always improve, and they could sometimes be even worse. Patients and their families should fully understand that subthalamic nucleus deep brain stimulation can alter the motor status and time is needed to readapt to their new postoperative state and lifestyles. This paper reviews the literatures regarding effects of bilateral subthalamic nucleus deep brain stimulation on social adjustment, quality of life and coping strategies in patients with Parkinson’s disease. The findings may help to understand the psychosocial maladjustment and poor improvement in quality of life in some Parkinson’s disease patients .