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作者曾从日本蝮蛇(Agkistrodon halys blomhoffii)中分离出平滑肌收缩活性肽blomhotin,并报道了其结构。为了研究该肽的构效关系,又对中国蝮蛇(Agkistrodon blomhoffii brevicaudus)是否存在类似肽进行了探讨,并在缓激肽增强肽(BPP)中合成了类似blomhotin的2种肽。
The authors isolated the smooth muscle contractile peptide bromhotin from Agkistrodon halys blomhoffii and reported its structure. In order to study the structure-activity relationship of this peptide, we also discussed the existence of similar peptides in Agkistrodon blomhoffii brevicaudus and synthesized two peptides similar to blomhotin in bradykinin-enhancing peptide (BPP).