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检测８９２例各类肝病患者血清中甲型（ＨＡＶ）、乙型（ＨＢＶ）、丙型（ＨＣＶ）、戊型（ＨＥＶ）肝炎病毒标志物。丙型肝炎患者占肝病患者１３．６％（１２１／８９２），其中５９．５％（７３／１２１）为重叠感染。ＨＣＶ与ＨＢＶ重叠感染最常见，占６４．６％（４７／７３），其次是ＨＣＶ、ＨＡＶ和ＨＢＶ（１３．７％），ＨＣＶ与ＨＥＶ（１８．２％），ＨＣＶ与ＨＡＶ（６．８％），及ＨＣＶ、ＨＢＶ和ＨＥＶ（６．８％）。ＨＣＶ重叠感染者重症肝炎生率及病死率均显著高于单纯ＨＣＶ感染者。结果提示，重叠感染是ＨＣＶ感染者病情恶化及死亡的重要因素。
Serum samples of hepatitis B virus (HBV), hepatitis B virus (HCV), hepatitis C virus (HEV) and hepatitis E virus (HEV) were detected in 892 cases of various liver diseases. Hepatitis C patients accounted for 13.6% (121/892) of patients with liver disease, of which 59.5% (73/121) were overlapping infections. Infection with HCV and HBV was the most common, accounting for 64.6% (47/73), followed by HCV, HAV and HBV (13.7%), HCV and HEV (18.2%), HCV and HAV %), And HCV, HBV and HEV (6.8%). The incidence of severe hepatitis and fatality rate in patients with overlapping HCV infection were significantly higher than those in HCV-infected patients. The results suggest that over-infection is an important factor in the progression of HCV infection and death.