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目的探讨亚麻醉剂量氯胺酮-芬太尼在小儿区域麻醉中的临床应用效果。方法选取2011年6月—2013年3月东台市时堰镇后港卫生院收治的52例手术患儿,依据患儿住院号尾数的奇偶数将其分为观察组27例和对照组25例。对照组患儿手术治疗中仅实施氯胺酮麻醉,观察组患儿手术治疗中实施氯胺酮-芬太尼区域麻醉,比较两组患儿的治疗时间、麻醉唤醒时间、氯胺酮用量以及追加次数等。结果观察组患儿的心率、平均动脉压以及呼吸频率均低于对照组,唤醒时间短于对照组,氯胺酮用量以及氯胺酮追加次数少于对照组,差异有统计学意义(P<0.05)。两组患儿的手术时间比较,差异无统计学意义(P>0.05)。结论亚麻醉剂量氯胺酮-芬太尼实施区域麻醉,能够明显缩短患儿的唤醒时间,减少生理干扰,麻醉用药安全。
Objective To investigate the clinical effect of sub-anesthetic ketamine-fentanyl in children’s regional anesthesia. Methods From June 2011 to March 2013, 52 surgical patients admitted to Hougang Hospital of Shi-wei Town, Dongtai City were divided into observation group (27 cases) and control group (25 cases) . In the control group, only ketamine anesthesia was performed in the surgical treatment. The ketamine-fentanyl anesthesia was performed during the surgical treatment of the children in the observation group. The treatment time, the anesthetic awakening time, the ketamine dosage and the additional times were compared between the two groups. Results The heart rate, mean arterial pressure and respiratory rate in observation group were lower than those in control group, and the awakening time was shorter than that in control group. The dosage of ketamine and the addition of ketamine were less than those in control group. The difference was statistically significant (P <0.05). There was no significant difference in operation time between the two groups (P> 0.05). Conclusion The sub-anesthetic dose of ketamine-fentanyl regional anesthesia can significantly shorten the wake-up time in children, reduce physical disturbance, anesthesia medication safety.