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目的:探讨妊娠期泌尿系结石成分组成,并根据其结果指导妊娠期女性进行泌尿系结石的治疗及预防。方法:收集我院2013年6月—2015年6月住院和门诊妊娠期泌尿系结石标本69例。其中61例通过输尿管镜从输尿管取出的结石,8例为门诊自行排出的结石,均采用红外线光谱检测法对其化学成分进行定性分析。结果:本组妊娠期泌尿系结石样本中碳酸磷灰石、一水草酸钙、二水草酸钙26例(38%);碳酸磷灰石、二水草酸钙、一水草酸钙11例(16%);一水草酸钙、二水草酸钙、碳酸磷灰石10例(14%);一水尿酸钠、一水草酸钙5例(7%);碳酸磷灰石、二水草酸钙4例(6%);黄嘌呤4例(6%),二水碳酸氢钙4例(6%);无水尿酸、一水草酸钙3例(4%);一水草酸钙2例(2.8%)。结论:妊娠期泌尿系结石的化学成分以碳酸磷灰石为主,与非妊娠期泌尿系结石常见的草酸钙化学成分有明显差异。
Objective: To investigate the composition of urinary stones during pregnancy and to guide the treatment and prevention of urolithiasis in pregnant women according to their results. Methods: Sixty-nine cases of urinary calculi during hospitalization and outpatient pregnancy in our hospital from June 2013 to June 2015 were collected. Sixty-one of them were removed from the ureter by ureteroscope, and eight were self-discharged stones. The chemical constituents were all qualitatively analyzed by infrared spectroscopy. Results: 26 cases (38%) of carbonic acid apatite, calcium oxalate monohydrate and calcium oxalate dihydrate in urinary calculi samples during pregnancy were found. Among them, there were 11 cases of carbonate apatite, calcium oxalate dihydrate and calcium oxalate monohydrate %); Calcium oxalate dihydrate, calcium oxalate dihydrate, carbonated apatite in 10 cases (14%); sodium urate monohydrate, calcium oxalate monohydrate in 5 cases (7%); carbonated apatite, calcium oxalate dihydrate 4 (6%); 4 cases of xanthine (6%), 4 cases of calcium bicarbonate dihydrate (6%); 3 cases of anhydrous uric acid and calcium oxalate monohydrate (4% %). Conclusion: The chemical composition of urinary calculi during pregnancy is mainly composed of carbonated apatite, which is obviously different from the common chemical components of calcium oxalate in non-pregnant urolithiasis.