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不明原因的肝硬化仍占美国漫性肝病的5％。在暴发性肝衰竭患者中，24％的成人和47％的儿童患者尚无确切原因。1997年Nishizawa等报告了一种新的DNA病毒与未明的原因（非甲一度型）肝炎患者转氨酶增高有关，这种病毒被命名为TT病毒（TTV）。TTV是一个无包膜的单链DNA病毒，全长3
Unidentified cirrhosis still accounts for 5% of American diffuse liver disease. In fulminant hepatic failure patients, 24% of adults and 47% of children with no exact reason. Nishizawa et al. Reported in 1997 that a new DNA virus was associated with increased transaminases in hepatitis patients with unexplained (non-first-degree) hepatitis and that the virus was named the TT virus (TTV). TTV is a non-enveloped single-stranded DNA virus, full-length 3