过去由于合霉素毒味極苦,小兒服后往往吐出,不能获得药效。药剂工作同志虽經多方努力,作成糖漿剂、合剂等,但苦味仍不能消除,在病兒服用时仍感到非常困难。我們試用作仁丹的方法將合霉素粉加入甘草粉作稀釋剂和匀,用5%—10%淀扮糊作黏合剂,过篩,使成小颗粒。篩下置一簸箕,上舖滑石粉或硬脂酸鎂,顆粒落下后,即迅速搖动,使成均匀的丸剂。搖成之后,用篩除去过大过小的丸,即得均匀一致的合霉素水丸(最好搖成之后,充分干燥,再上一層滑石衣,則毫無苦味)。过大过小的丸剂,經粉碎以后再过篩,在簸箕中 In the past, due to the extremely bitter taste of zeocin, pediatric patients often spit out after serving and cannot obtain the efficacy. Although the comrades working in the pharmaceutical industry have made many efforts to make syrups and mixtures, the bitter taste cannot be eliminated and it is still very difficult for the sick children to take them. We tried to use Rendan’s method to add zeocin powder to the licorice powder as a diluent and uniform, use 5%-10% of the lake as a binder, sifting, and make it into small particles. Place a sieve under the top and lay talcum powder or magnesium stearate. After the particles fall, they are quickly shaken to make a homogeneous pellet. After shaking, the oversized and small pellets are removed with a sieve to obtain uniform and uniform water pills of methammycin (preferably after shaking, drying thoroughly, and then applying a layer of talc, there is no bitterness). Pills that are too big and too small, crushed and then sifted,