随着血栓性血小板减少性紫癜(TTP)病理生理的进一步阐明及新疗法的开展,本症预后有了显著改善。一、TTP的临床表现:TTP以溶血性贫血、血小板减少、多变性神经症状、发热、肾脏损害五大症候为临床特征。发病年龄10-40岁,女性稍多见(60%)。典型病例在乏力、关节痛等前驱症状后迅速出现贫血、黄疸、出血倾向。几乎都有发热,与此同时有痉挛、知觉障碍及意识障碍等神经症状。神经症状初期有一过性及多变性的特征,随着疾病的进展而陷入昏迷。有急性肾功不全的表现。急性经过 With thrombotic thrombocytopenic purpura (TTP) pathophysiology to further clarify and the new treatment, the prognosis of this disease has been significantly improved. First, the clinical manifestations of TTP: TTP with hemolytic anemia, thrombocytopenia, variability of neurological symptoms, fever, kidney damage five major clinical symptoms. The age of onset of 10-40 years old, slightly more women (60%). Typical cases of anemia, jaundice, bleeding tendency rapidly after the prodromal symptoms such as fatigue and joint pain. Almost all have fever, at the same time there are spasms, cognitive disorders and disturbance of consciousness and other neurological symptoms. Early neurological symptoms have a transient and variability, with the progress of the disease and into a coma. Acute renal insufficiency of the performance. Acute after