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采取随机、双盲、对照的方法对48例急性黄疸型病毒性肝炎进行疗效对比研究,治疗组25例,应用小剂量山莨菪碱加传统治疗药物;对照组23例,单用传统护肝、对症、支持治疗药物。经15、30天的治疗观察,发现治疗组临床症状消失快,TB、TTT、GPT三项指标显著低于对照组(P<0.05或<0.01);有效率治疗组为96.00%,对照组为60.87%,两组疗效有非常显著差异(P<0.01),显示应用山莨菪碱优于传统治疗方法。建议在制定各型病毒性肝炎治疗方案中,应把山莨菪碱作为常规治疗药物。由于山莨菪碱疗效满意,经济安全,适宜在基层医疗单位应用和推广。
A randomized, double-blind, control of 48 cases of acute jaundice viral hepatitis efficacy comparison study, the treatment group of 25 patients, the application of low-dose anisodamine plus traditional treatment drugs; control group of 23 patients with single traditional liver protection, Symptomatic, support for the treatment of drugs. After 15 and 30 days of treatment, the clinical symptoms of the treatment group disappeared rapidly, and the indexes of TB, TTT and GPT were significantly lower than those of the control group (P <0.05 or <0.01). The effective rate of the treatment group was 96. 00% in the control group and 60.87% in the control group. There was a significant difference between the two groups (P <0.01), indicating that anisodamine was superior to the traditional treatment. Proposed in the development of various types of viral hepatitis treatment programs, should be anisodamine as a conventional treatment. As the efficacy of anisodamine, economic security, suitable for application and promotion of primary medical units.