论文部分内容阅读
目的探讨宫颈癌患者多次计划CT引导的三维近距离治疗可行性及对危及器官剂量关系。方法 10例接受根治性放疗的Ⅲb期宫颈癌患者每次腔内放疗前行CT扫描并勾画高危临床靶体积(HRCTV)及膀胱、直肠。危及器官采用D2cm3评价。处方剂量A点6 Gy单次后进行几何优化,直肠D2cm3≤4.2 Gy,膀胱D2cm3≤5.2Gy。治疗结束统计膀胱及直肠受照射的具体剂量。结果 10例患者的6~7次三维腔内后装治疗中,膀胱、直肠D2cm3的受照射剂量分布是非均一性的,受照射剂量变化范围较大。结论 CT引导下的宫颈癌三维近距离治疗中多次计划有必要,更加精确且个体化。
Objective To investigate the feasibility of CT-guided three-dimensional brachytherapy in patients with cervical cancer and its relationship with the organ dose at risk. Methods Ten patients with stage Ⅲb cervical cancer undergoing radical radiotherapy were treated with CT scan and high-risk clinical target volume (HRCTV) and bladder and rectum before each intracavitary radiotherapy. Endangered organs using D2cm3 evaluation. Prescription dose A point 6 Gy geometric optimization after a single, rectum D2cm3 ≤ 4.2 Gy, bladder D2cm3 ≤ 5.2Gy. The end of treatment statistics bladder and rectal irradiation specific dose. Results In 10 cases of 6 to 7 times three-dimensional intracavitary after-treatment, bladder, rectum D2cm3 irradiation dose distribution is non-uniform, subject to a larger range of doses. Conclusions CT-guided cervical cancer three-dimensional brachytherapy in multiple planning is necessary, more accurate and individualized.