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目的:比较分析放化疗与介入性动脉化疗治疗局部晚期动脉宫颈癌的临床效果。方法:选择我院局部晚期宫颈癌患者97例,依据治疗方法分为常规组(行传统放化疗)55例和介入组(行介入性动脉化疗)42例。观察治疗后肿瘤大小、近期疗效、根治性手术率、术后并发症,对生活质量指数进行评分,评价两种方法的临床效果。结果:治疗后,两组患者近期疗效比较差异无统计学意义(P>0.05);介入组肿瘤直径明显小于常规组,而根治性手术率明显高于常规组,差异均具有统计学意义(P<0.05);介入组患者日常生活、健康、总体情况以及总的评分均明显高于常规组,差异具有统计学意义(P<0.05),同时介入组并发症较少。结论:放化疗与介入性动脉化疗治疗局部晚期动脉宫颈癌近期临床疗效均较好,但介入性动脉化疗具有较高的根治性手术率以及生活质量,且并发症少。
Objective: To compare the clinical effects of chemoradiation and interventional arterial chemotherapy in the treatment of locally advanced cervical cancer. Methods: Ninety-seven patients with locally advanced cervical cancer in our hospital were selected and divided into 55 cases of conventional radiotherapy and chemotherapy and 42 cases of interventional arterial chemotherapy according to the method of treatment. The tumor size, short-term curative effect, radical operation rate and postoperative complications were observed after treatment. The quality of life index was scored and the clinical effects of the two methods were evaluated. Results: There was no significant difference in short-term curative effect between the two groups after treatment (P> 0.05). The diameter of tumor in the intervention group was significantly smaller than that in the conventional group, while the radical operation rate was significantly higher than that in the conventional group (P <0.05). The daily life, health, general condition and overall score of intervention group were significantly higher than those of routine group (P <0.05). At the same time, there were fewer complications in intervention group. Conclusion: The recent clinical curative effects of radiotherapy and chemotherapy and interventional arterial chemotherapy for locally advanced cervical cancer are good. However, interventional arterial chemotherapy has a high rate of radical surgery and quality of life with few complications.