早在1918年Zondck首先描述了甲状腺机能减退病人的心脏损害,报道了4例粘液性水肿伴心脏扩大病人的心电图示有低QRS波及平坦或倒置的T波。随后Gordon等在1929报道了粘液性水肿病人可发生心包积液,从而引起了临床医生及病理学家的重视,开始对粘液性水肿性心脏病人的临床表现及 As early as 1918, Zondck first described the cardiac damage in patients with hypothyroidism. It was reported in 4 patients with myxedema and cardiac enlargement that the ECG showed low QRS and flat or inverted T wave. Then Gordon et al reported in 1929 that patients with myxedema may develop pericardial effusion, which has attracted the attention of clinicians and pathologists, began to clinical manifestations of myxedema patients with heart disease and