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目的探讨盐酸氨溴索对矽肺合并呼吸道感染的临床疗效,为治疗提供依据。方法随机选矽肺合并呼吸道感染患者45例为治疗组,在常规治疗基础上,加用盐酸氨溴索进行治疗,观察感染控制时间和治疗效果,对数据进行分析。结果用盐酸氨溴索的治疗组感染控制时间明显短于对照组(P<0.05)。治疗组总有效率为88.89%,明显高于对照组的61.29%(P<0.05)。结论用盐酸氨溴索可明显提高矽肺合并呼吸道感染的临床疗效。
Objective To investigate the clinical efficacy of ambroxol hydrochloride in patients with silicosis complicated with respiratory tract infection and provide the basis for treatment. Methods Forty-five patients with silicosis and respiratory tract infection were selected as the treatment group. Ambroxol hydrochloride was added to the treatment group on the basis of conventional treatment. The time of infection control and the therapeutic effect were observed. The data were analyzed. Results The duration of infection control in ambroxol hydrochloride group was significantly shorter than that in control group (P <0.05). The total effective rate of the treatment group was 88.89%, which was significantly higher than that of the control group (61.29%, P <0.05). Conclusion Ambroxol hydrochloride can significantly improve the clinical efficacy of silicosis and respiratory tract infection.