骨巨细胞瘤一般认为起源于中胚叶组织的破骨细胞 ,多发生于长骨骨骺部 ,其次为椎骨、肋骨、盆骨 ,而原发于颅底的骨巨细胞瘤则属少见。结合在临床实践中对颅底骨巨细胞瘤的诊断经验并复习了文献报道 ,对颅底骨巨细胞瘤的临床、病理及影像学表现进行综述 ,旨在加深对颅底骨巨细 Giant cell tumor of bone is generally considered to originate in the mesodermal tissue of osteoclasts, mostly in the long bone epiphysis, followed by vertebrae, ribs, pelvis, while the primary cranial base of giant cell tumor is rare. Combined with clinical experience in diagnosis of skull base giant cell tumor and review the literature reported on the skull base giant cell tumor clinical, pathological and imaging findings are reviewed to deepen the skull base bone size