以疏水性高分子材料为基质的普通完整缓释片一般符合一级或HigUchi动力学，借膨胀或溶蚀机理的亲水性基质中药物释放也往往符合HigUchi动力学或偏离零级动力学，都难以长时间（＞20小时）达到零级释放。有报道通过包含孔膜衣、渗透泵、多层片或控制缓释片的几何形状等方式可以? Common, sustained-release tablets based on hydrophobic polymeric materials generally conform to either first-order or HigUchi kinetics, and drug release in hydrophilic matrices, either by swelling or dissolution mechanisms, also tends to meet HigUchi kinetics or deviate from zero-order kinetics, both It is difficult to achieve zero-level release for a long time (> 20 hours). It has been reported that by including pore membrane clothing, osmotic pumps, multi-layer tablets or control the release of the geometry of the plate and so on?