冠心监护病房的最早记述提示,所有发生心室颤动或致命室性心动过速的病人均有“先兆性心律失常”,例如频繁室性过早搏动,R落在T波上的室性过早搏动,成对或多源性室性过早搏动,短程室性心动过速。进而又指出,此种所谓先兆性心律失常能够在发现后加以抑制,从而完全防止原发性心室颤动。由此产生了应用利多卡因的治疗方案,并广泛应用于冠心监护病房。其后,一些医疗中心对先兆性心律失常的概念进行了研究。虽然许多心室颤动发作可能先有这种心律失常,但25～50％的冠心监护病房患者在首次发作心室颤动前,并无明确的先兆性心 Earliest documented coronary care units suggest that all patients with ventricular fibrillation or fatal ventricular tachycardia have “precursory arrhythmias,” such as frequent ventricular premature beats, R falls on the T wave of premature ventricular contractions Dynamic, paired or multi-ventricular premature beats, short-range ventricular tachycardia. Furthermore, it is pointed out that this so-called precursor arrhythmia can be suppressed after the discovery, thus completely preventing the primary ventricular fibrillation. This led to the use of lidocaine treatment options and is widely used in coronary care units. Since then, some medical centers have studied the concept of atrial arrhythmia. Although many arrhythmias may occur with many episodes of ventricular fibrillation, 25 to 50% of patients in a CHD have no definite precursors before the first episode of ventricular fibrillation