本文报道葡萄球菌 A蛋白协同凝集(SPA COA)快速检测草鱼出血病病毒的方法以及对提纯病毒、染毒细胞内病毒和病鱼组织检测的初步结果。并对该方法进行了特异性和敏感性考核以及凝集物的电镜观察。该方法快速、特异、设备简单,适合基层单位检测草鱼出血病病毒,并有可能作为草鱼出血病疫苗质量鉴定的指标之一。 This article reports the method of rapid detection of grass carp hemorrhagic disease virus by Staphylococcus A Protein Synergistic Agglutination (SPA COA) and the preliminary results of the detection of the purified virus, intracellular virus and diseased fish tissue. The specificity and sensitivity of the method and the electron microscopy of agglutinates were also studied. The method is rapid, specific and simple in equipment. It is suitable for detecting grass carp hemorrhagic disease virus in grassroots units and may be used as an indicator of the quality identification of the grass carp hemorrhagic disease vaccine.