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目的巨幼细胞性贫血(巨幼贫)病人血乳酸脱氢酶(LDH)及血α-羟丁酸脱氢酶(a-HB-DH)明显升高,提醒非血液科医生注意,避免误诊。方法对2004年5月至2005年12月诊断的30例巨幼贫病人进行心肌酶学测定。其他血液病病人30例作为对照组。结果巨幼贫病人 LDH 及α-HBDH 明显升高,血天冬氨酸转氨酶(AST)、血肌酸激酶(CPK)及血肌酸激酶同工酶(CK-MB)正常或轻度升高。对照组LDH 及α-HBDH 不高或轻度升高。结论巨幼贫病人 LDH 及 a-HBDH 明显升高。
Objectives The patients with megaloblastic anemia (megaloblastic poor) have significantly increased blood lactate dehydrogenase (LDH) and blood a-hydroxybutyrate dehydrogenase (a-HB-DH), reminding non-hematologists to avoid misdiagnosis . Methods Thirty cases of megaloblastic patients diagnosed from May 2004 to December 2005 were tested for myocardial enzymology. Thirty patients with other hematological diseases served as control group. Results The levels of LDH and α-HBDH in patients with meiosis were significantly higher than those in patients without melatonin, and the levels of AST, CKK and CK-MB were normal or slightly elevated . The control group LDH and α-HBDH low or slightly elevated. Conclusion The levels of LDH and a-HBDH in megaloblastic patients are significantly higher.